Macula Society 45th Annual Meeting

Professor Giovanni Staurenghi presented collaborative work on the “Automated quantitative assessment of neovascular age-related macular degeneration ocular coherence tomography (OCT) images acquired using a home-based OCT device” at today’s session on neovascular AMD.  The work details the performance of a prototype home OCT device used to capture 136 subject eyes with neovascular AMD.  Voxeleron’s analysis tools were used to segment and quantify the retinal layers as well as intra-retinal, sub-retinal and fluid beneath the retinal pigment epithelium (RPE) layer.  The segmentation was run on all three devices – the prototype home device and two clinical devices (see example slide below) – and the performance was deemed akin to human graders with image quality on a par to the clinical devices.  The conclusions were:

  • Automated analysis of the images acquired using the prototype home OCT device achieved a high degree of accuracy for retinal layer segmentation, retinal fluid detection, and retinal fluid quantification across all retinal fluid types in comparison with manually generated measurements
  • This is an important foundation for future studies of the prototype home OCT device and highlights its potential to detect the need for anti-VEGF retreatment outside the clinic

Further information can be found here:

Macula Society Meeting
Slide from the presentation showing Spectralis data (A), Home OCT data (B) and Cirrus data (C). To the right of these example images are Voxeleron’s automated segmentation of the retina and the retinal fluid (red – intra-retinal; blue – sub-retinal; and green – sub-RPE).